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Crystallographic study of G178S mutant of human proliferating cell nuclear antigen

Proliferating cell nuclear antigen (PCNA) is an evolutionarily conserved protein that forms a ring-shaped homotrimer that functions as a sliding clamp for DNA replication. The rev6-1 mutation of Saccharomyces cerevisiae, which inactivates both translesion DNA synthesis and damage-avoidance pathways...

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Detalhes bibliográficos
Main Authors: Hishiki, Asami, Shimizu, Toshiyuki, Serizawa, Aya, Ohmori, Haruo, Sato, Mamoru, Hashimoto, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531271/
https://ncbi.nlm.nih.gov/pubmed/18765913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910802277X
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