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Crystallization and X-ray diffraction analysis of the ternary complex of the C-terminal domain of human REV1 in complex with REV7 bound to a REV3 fragment involved in translesion DNA synthesis

REV1, REV3 and REV7 are pivotal proteins in translesion DNA synthesis that allows DNA synthesis to continue even in the presence of DNA damage. REV1 and REV3 are error-prone DNA polymerases, while REV7 acts as an adaptor protein that links them together. A ternary complex of the C-terminal domain of...

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Detalhes bibliográficos
Main Authors: Kikuchi, Sotaro, Hara, Kodai, Shimizu, Toshiyuki, Sato, Mamoru, Hashimoto, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412784/
https://ncbi.nlm.nih.gov/pubmed/22869133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112032435
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