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Purification, crystallization and initial X-ray diffraction study of human REV7 in complex with a REV3 fragment

REV7 is involved in various cellular functions including DNA replication, signal transduction and cell-cycle regulation. In DNA replication, REV7 interacts with REV3 and forms DNA polymerase ζ, which plays a central role in error-prone DNA synthesis. REV3 is a catalytic subunit and its activity is s...

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Detalhes bibliográficos
Main Authors: Hara, Kodai, Shimizu, Toshiyuki, Unzai, Satoru, Akashi, Satoko, Sato, Mamoru, Hashimoto, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802887/
https://ncbi.nlm.nih.gov/pubmed/20054135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109046181
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