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Purification, crystallization and initial X-ray diffraction study of human REV7 in complex with a REV3 fragment
REV7 is involved in various cellular functions including DNA replication, signal transduction and cell-cycle regulation. In DNA replication, REV7 interacts with REV3 and forms DNA polymerase ζ, which plays a central role in error-prone DNA synthesis. REV3 is a catalytic subunit and its activity is s...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
International Union of Crystallography
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802887/ https://ncbi.nlm.nih.gov/pubmed/20054135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109046181 |
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