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Crystal structure and functional implication of the RUN domain of human NESCA

NESCA, a newly discovered signaling adapter protein in the NGF-pathway, contains a RUN domain at its N-terminus. Here we report the crystal structure of the NESCA RUN domain determined at 2.0-Å resolution. The overall fold of the NESCA RUN domain comprises nine helices, resembling the RUN domain of...

詳細記述

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書誌詳細
出版年:Protein Cell
主要な著者: Sun, Qifan, Han, Chuanhui, Liu, Lan, Wang, Yizhi, Deng, Hongyu, Bai, Lin, Jiang, Tao
フォーマット: Artigo
言語:Inglês
出版事項: Higher Education Press 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875354/
https://ncbi.nlm.nih.gov/pubmed/22821014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-012-2052-3
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