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Perspectives on the role of mTORC2 in B lymphocyte development, immunity and tumorigenesis

Mammalian target of rapamycin complex 2 (mTORC2) is a key downstream mediator of phosphoinositol-3-kinase (PI3K) dependent growth factor signaling. In lymphocytes, mTORC2 has emerged as an important regulator of cell development, homeostasis and immune responses. However, our current understanding o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Protein Cell
Prif Awduron: Lazorchak, Adam S., Su, Bing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Higher Education Press 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875240/
https://ncbi.nlm.nih.gov/pubmed/21822797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1077-3
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