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Perspectives on the role of mTORC2 in B lymphocyte development, immunity and tumorigenesis
Mammalian target of rapamycin complex 2 (mTORC2) is a key downstream mediator of phosphoinositol-3-kinase (PI3K) dependent growth factor signaling. In lymphocytes, mTORC2 has emerged as an important regulator of cell development, homeostasis and immune responses. However, our current understanding o...
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| Publié dans: | Protein Cell |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Higher Education Press
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875240/ https://ncbi.nlm.nih.gov/pubmed/21822797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1077-3 |
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