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Bacterial outer membrane vesicles mediate cytosolic localization of LPS and caspase-11 activation
Sensing of lipopolysaccharide (LPS) in the cytosol triggers caspase-11 activation and is central to host defense against Gram-negative bacterial infections and to the pathogenesis of sepsis. Most Gram-negative bacteria that activate caspase-11 however are not cytosolic and the mechanism by which LPS...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4874922/ https://ncbi.nlm.nih.gov/pubmed/27156449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.015 |
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