The pro-inflammatory effects of miR-155 promote liver fibrosis and alcohol-induced steatohepatitis

BACKGROUND & AIMS: Alcoholic liver disease (ALD) ranges from fatty liver to inflammation and cirrhosis. miRNA-155 is an important regulator of inflammation. In this study, we describe the in vivo role of miR-155 in ALD. METHODS: Wild type, WT (C57/BL6J) or miR-155 KO and TLR4 KO mice received Li...

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Udgivet i:J Hepatol
Main Authors: Bala, Shashi, Csak, Timea, Saha, Banishree, Zatsiorsky, James, Kodys, Karen, Catalano, Donna, Szabo, Gyongyi
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874886/
https://ncbi.nlm.nih.gov/pubmed/26867493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2016.01.035
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