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Combined treatment with epigenetic, differentiating, and chemotherapeutic agents cooperatively targets tumor-initiating cells in triple negative breast cancer

Efforts to induce the differentiation of cancer stem cells through treatment with all-trans retinoic acid (ATRA) have yielded limited success, partially due to the epigenetic silencing of the retinoic acid receptor (RAR)-β. The histone deacetylase inhibitor, entinostat, is emerging as a promising an...

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書誌詳細
出版年:Cancer Res
主要な著者: Merino, Vanessa F., Nguyen, Nguyen, Jin, Kideok, Sadik, Helen, Cho, Soonweng, Korangath, Preethi, Han, Liangfeng, Foster, Yolanda M. N., Zhou, Xian C., Zhang, Zhe, Connolly, Roisin M., Stearns, Vered, Ali, Syed Z., Adams, Christina, Chen, Qian, Pan, Duojia, Huso, David L., Ordentlich, Peter, Brodie, Angela, Sukumar, Saraswati
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873448/
https://ncbi.nlm.nih.gov/pubmed/26787836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1619
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