HEYL Regulates Neoangiogenesis Through Overexpression in Both Breast Tumor Epithelium and Endothelium

Blocking tumor angiogenesis is an appealing therapeutic strategy, but to date, success has been elusive. We previously identified HEYL, a downstream target of Notch signaling, as an overexpressed gene in both breast cancer cells and as a tumor endothelial marker, suggesting that HEYL overexpression...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Han, Liangfeng, Korangath, Preethi, Nguyen, Nguyen K., Diehl, Adam, Cho, Soonweng, Teo, Wei Wen, Cope, Leslie, Gessler, Manfred, Romer, Lewis, Sukumar, Saraswati
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845423/
https://ncbi.nlm.nih.gov/pubmed/33520697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.581459
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