HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24

Loss of HOXA5 expression occurs frequently in breast cancer and correlates with higher pathological grade and poorer disease outcome. However, how HOX proteins drive differentiation in mammalian cells is poorly understood. In this paper, we investigated cellular and molecular consequences of loss of...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Teo, Wei Wen, Merino, Vanessa F., Cho, Soonweng, Korangath, Preethi, Liang, Xiaohui, Wu, Ren-chin, Neumann, Neil M., Ewald, Andrew J., Sukumar, Saraswati
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073039/
https://ncbi.nlm.nih.gov/pubmed/27157614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.95
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