HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24

Loss of HOXA5 expression occurs frequently in breast cancer and correlates with higher pathological grade and poorer disease outcome. However, how HOX proteins drive differentiation in mammalian cells is poorly understood. In this paper, we investigated cellular and molecular consequences of loss of...

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Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Teo, Wei Wen, Merino, Vanessa F., Cho, Soonweng, Korangath, Preethi, Liang, Xiaohui, Wu, Ren-chin, Neumann, Neil M., Ewald, Andrew J., Sukumar, Saraswati
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073039/
https://ncbi.nlm.nih.gov/pubmed/27157614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.95
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