HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24

Loss of HOXA5 expression occurs frequently in breast cancer and correlates with higher pathological grade and poorer disease outcome. However, how HOX proteins drive differentiation in mammalian cells is poorly understood. In this paper, we investigated cellular and molecular consequences of loss of...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Oncogene
Главные авторы: Teo, Wei Wen, Merino, Vanessa F., Cho, Soonweng, Korangath, Preethi, Liang, Xiaohui, Wu, Ren-chin, Neumann, Neil M., Ewald, Andrew J., Sukumar, Saraswati
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073039/
https://ncbi.nlm.nih.gov/pubmed/27157614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.95
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы