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Epigenetics as a Therapeutic Target in Breast Cancer

Epigenetics refers to alterations in gene expression due to modifications in histone acetylation and DNA methylation at the promoter regions of genes. Unlike genetic mutations, epigenetic alterations are not due to modifications in the gene primary nucleotide sequence. The importance of epigenetics...

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Detalhes bibliográficos
Main Authors: Connolly, Roisin, Stearns, Vered
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515719/
https://ncbi.nlm.nih.gov/pubmed/22836913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10911-012-9263-3
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