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EPIGENETIC TARGETING IN BREAST CANCER: THERAPEUTIC IMPACT AND FUTURE DIRECTION
Breast carcinogenesis is a multistep process involving both genetic and epigenetic changes. Epigenetics is defined as a reversible and heritable change in gene expression that is not accompanied by alteration in gene sequence. DNA methylation and histone modifications are the two major epigenetic ch...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3658161/ https://ncbi.nlm.nih.gov/pubmed/19890494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1358/dnp.2009.22.7.1405072 |
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