Conducting a Virtual Clinical Trial in HER2-Negative Breast Cancer Using a Quantitative Systems Pharmacology Model With an Epigenetic Modulator and Immune Checkpoint Inhibitors

The survival rate of patients with breast cancer has been improved by immune checkpoint blockade therapies, and the efficacy of their combinations with epigenetic modulators has shown promising results in preclinical studies. In this prospective study, we propose an ordinary differential equation (O...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Front Bioeng Biotechnol
Huvudupphovsmän: Wang, Hanwen, Sové, Richard J., Jafarnejad, Mohammad, Rahmeh, Sondra, Jaffee, Elizabeth M., Stearns, Vered, Torres, Evanthia T. Roussos, Connolly, Roisin M., Popel, Aleksander S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020
Ämnen:
Bioengineering and Biotechnology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051945/
https://ncbi.nlm.nih.gov/pubmed/32158754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00141
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk