Conducting a Virtual Clinical Trial in HER2-Negative Breast Cancer Using a Quantitative Systems Pharmacology Model With an Epigenetic Modulator and Immune Checkpoint Inhibitors

The survival rate of patients with breast cancer has been improved by immune checkpoint blockade therapies, and the efficacy of their combinations with epigenetic modulators has shown promising results in preclinical studies. In this prospective study, we propose an ordinary differential equation (O...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Bioeng Biotechnol
Egile Nagusiak: Wang, Hanwen, Sové, Richard J., Jafarnejad, Mohammad, Rahmeh, Sondra, Jaffee, Elizabeth M., Stearns, Vered, Torres, Evanthia T. Roussos, Connolly, Roisin M., Popel, Aleksander S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2020
Gaiak:
Bioengineering and Biotechnology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051945/
https://ncbi.nlm.nih.gov/pubmed/32158754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00141
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