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Epigenetics as a Therapeutic Target in Breast Cancer

Epigenetics refers to alterations in gene expression due to modifications in histone acetylation and DNA methylation at the promoter regions of genes. Unlike genetic mutations, epigenetic alterations are not due to modifications in the gene primary nucleotide sequence. The importance of epigenetics...

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Bibliografiske detaljer
Main Authors: Connolly, Roisin, Stearns, Vered
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515719/
https://ncbi.nlm.nih.gov/pubmed/22836913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10911-012-9263-3
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