Induction of cell cycle arrest and inflammatory genes by combined treatment with epigenetic, differentiating, and chemotherapeutic agents in triple-negative breast cancer

BACKGROUND: A combination of entinostat, all-trans retinoic acid, and doxorubicin (EAD) induces cell death and differentiation and causes significant regression of xenografts of triple-negative breast cancer (TNBC). METHODS: We investigated the mechanisms underlying the antitumor effects of each com...

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Publicado en:Breast Cancer Res
Autores principales: Merino, Vanessa F., Cho, Soonweng, Nguyen, Nguyen, Sadik, Helen, Narayan, Athira, Talbot, Conover, Cope, Leslie, Zhou, Xian C., Zhang, Zhe, Győrffy, Balázs, Sukumar, Saraswati
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263070/
https://ncbi.nlm.nih.gov/pubmed/30486871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-1068-x
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