Structural insights into DNA sequence recognition by Type ISP restriction-modification enzymes

Engineering restriction enzymes with new sequence specificity has been an unaccomplished challenge, presumably because of the complexity of target recognition. Here we report detailed analyses of target recognition by Type ISP restriction-modification enzymes. We determined the structure of the Type...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Kulkarni, Manasi, Nirwan, Neha, van Aelst, Kara, Szczelkun, Mark D., Saikrishnan, Kayarat
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872093/
https://ncbi.nlm.nih.gov/pubmed/26975655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw154
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