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DNA cleavage by Type ISP Restriction–Modification enzymes is initially targeted to the 3′-5′ strand
The mechanism by which a double-stranded DNA break is produced following collision of two translocating Type I Restriction–Modification enzymes is not fully understood. Here, we demonstrate that the related Type ISP Restriction–Modification enzymes LlaGI and LlaBIII can cooperate to cleave DNA follo...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553963/ https://ncbi.nlm.nih.gov/pubmed/23221632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1210 |
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