Dose escalation with over-dose and under-dose controls in Phase I/II clinical trials

To save valuable time and resources in new drug development, Phase I/II clinical trials with toxicity control and drug efficacy as dual primary endpoints have become increasingly popular. Escalation with over-dose control (the EWOC) is a Bayesian adaptive Phase I clinical trial design that can accur...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Contemp Clin Trials
Main Authors: Chen, Zhengjia, Yuan, Ying, Li, Zheng, Kutner, Michael, Owonikoko, Taofeek, Curran, Walter J., Khuri, Fadlo, Kowalski, Jeanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871606/
https://ncbi.nlm.nih.gov/pubmed/26012358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2015.05.014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados