Escalation with Overdose Control using All Toxicities and Time to Event Toxicity Data in Cancer Phase I Clinical Trials

The primary purposes of Phase I cancer clinical trials are to determine the maximum tolerated dose (MTD) and the treatment schedule of a new drug. Phase I trials usually involve a small number of patients so that fully utilizing all toxicity information including time to event toxicity data is key t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Chen, Zhengjia, Cui, Ye, Owonikoko, Taofeek K, Wang, Zhibo, Li, Zheng, Luo, Ruiyan, Kutner, Michael, Khuri, Fadlo R, Kowalski, Jeanne
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046505/
https://ncbi.nlm.nih.gov/pubmed/24530487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2014.02.004
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker