Caricamento...

Adaptive Estimation of Personalized Maximum Tolerated Dose in Cancer Phase I Clinical Trials Based on All Toxicities and Individual Genomic Profile

BACKGROUND: Many biomarkers have been shown to be associated with the efficacy of cancer therapy. Estimation of personalized maximum tolerated doses (pMTDs) is a critical step toward personalized medicine, which aims to maximize the therapeutic effect of a treatment for individual patients. In this...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Chen, Zhengjia, Li, Zheng, Zhuang, Run, Yuan, Ying, Kutner, Michael, Owonikoko, Taofeek, Curran, Walter J., Kowalski, Jeanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268707/
https://ncbi.nlm.nih.gov/pubmed/28125617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170187
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !