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A Molecular Mechanism to Regulate Lysosome Motility for Lysosome Positioning and Tubulation
To mediate the degradation of bio-macromolecules, lysosomes must traffic towards cargo-carrying vesicles for subsequent membrane fusion or fission. Mutations of the lysosomal Ca(2+) channel TRPML1 cause lysosome storage disease (LSD) characterized by disordered lysosomal membrane trafficking in cell...
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| 出版年: | Nat Cell Biol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4871318/ https://ncbi.nlm.nih.gov/pubmed/26950892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3324 |
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