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A voltage-dependent K(+) channel in the lysosome is required for refilling lysosomal Ca(2+) stores

The resting membrane potential (Δψ) of the cell is negative on the cytosolic side and determined primarily by the plasma membrane’s selective permeability to K(+). We show that lysosomal Δψ is set by lysosomal membrane permeabilities to Na(+) and H(+), but not K(+), and is positive on the cytosolic...

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Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Wang, Wuyang, Zhang, Xiaoli, Gao, Qiong, Lawas, Maria, Yu, Lu, Cheng, Xiping, Gu, Mingxue, Sahoo, Nirakar, Li, Xinran, Li, Ping, Ireland, Stephen, Meredith, Andrea, Xu, Haoxing
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461029/
https://ncbi.nlm.nih.gov/pubmed/28468834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201612123
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