A carregar...

Mutations, kataegis, and translocations in B lymphocytes: towards a mechanistic understanding of AID promiscuous activity

As B cells engage in the immune response they express the deaminase AID to initiate the hypermutation and recombination of immunoglobulin genes, which are crucial processes for the efficient recognition and disposal of pathogens, However, AID must be tightly controlled in B cells to minimize off-tar...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Rev Immunol
Main Authors: Casellas, Rafael, Basu, Uttiya, Yewdell, William T., Chaudhuri, Jayanta, Robbiani, Davide F., Di Noia, Javier M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871114/
https://ncbi.nlm.nih.gov/pubmed/26898111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri.2016.2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!