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Regulation of the fetal hemoglobin silencing factor BCL11A
The clinical severity of sickle cell disease and β-thalassemia, the major disorders of β-globin, can be ameliorated by increased production of fetal hemoglobin (HbF). Here, we provide a brief overview of the fetal-to-adult hemoglobin switch that occurs in humans shortly after birth and review our cu...
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| Publicado en: | Ann N Y Acad Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4870126/ https://ncbi.nlm.nih.gov/pubmed/26963603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.13024 |
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