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Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A
Reactivation of fetal hemoglobin (HbF) in adults ameliorates the severity of the common β-globin disorders. The transcription factor BCL11A is a critical modulator of hemoglobin switching and HbF silencing, yet the molecular mechanism through which BCL11A coordinates the developmental switch is inco...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631619/ https://ncbi.nlm.nih.gov/pubmed/23576758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303976110 |
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