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The transcription factors Slug (SNAI2) and Snail (SNAI1) regulate phospholipase D (PLD) promoter in opposite ways towards cancer cell invasion

Slug (SNAI2) and Snail (SNAI1) are master regulatory transcription factors for organogenesis and wound healing, and they are involved in the epithelial to mesenchymal transition (EMT) of cancer cells. We found that the activity of phospholipase D isoform 2 (PLD2) is highly increased in cancers with...

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Publicado en:Mol Oncol
Main Authors: Ganesan, Ramya, Mallets, Elizabeth, Gomez-Cambronero, Julian
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870114/
https://ncbi.nlm.nih.gov/pubmed/26781944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.12.006
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