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The transcription factors Slug (SNAI2) and Snail (SNAI1) regulate phospholipase D (PLD) promoter in opposite ways towards cancer cell invasion

Slug (SNAI2) and Snail (SNAI1) are master regulatory transcription factors for organogenesis and wound healing, and they are involved in the epithelial to mesenchymal transition (EMT) of cancer cells. We found that the activity of phospholipase D isoform 2 (PLD2) is highly increased in cancers with...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Ganesan, Ramya, Mallets, Elizabeth, Gomez-Cambronero, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870114/
https://ncbi.nlm.nih.gov/pubmed/26781944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.12.006
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