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Down-regulation of MicroRNAs (MiRs) 203, 887, 3619 and 182 Prevents Vimentin-triggered, Phospholipase D (PLD)-mediated Cancer Cell Invasion

Breast cancer is a leading cause of morbidity and mortality among women. Metastasis is initiated after epithelial-mesenchymal-transition (EMT). We have found a connection between EMT markers and the expression of four microRNAs (miRs) mediated by the signaling enzyme phospholipase D (PLD). Low aggre...

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Vydáno v:J Biol Chem
Hlavní autoři: Fite, Kristen, Gomez-Cambronero, Julian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705392/
https://ncbi.nlm.nih.gov/pubmed/26567912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.686006
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