Loading...

KIR3DL1 and HLA-B density and binding calibrate NK education and response to HIV

Natural killer (NK) cells recognize “self” HLA via killer Ig-like receptors (KIR). Homeostatic HLA expression signals for inhibition via KIR, and downregulation of HLA, a common consequence of viral infection, allows NK activation. Like HLA, KIR are highly polymorphic, and allele combinations of the...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Boudreau, Jeanette E., Mulrooney, Tiernan J., Le Luduec, Jean-Benoît, Barker, Edward, Hsu, Katharine C.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868784/
https://ncbi.nlm.nih.gov/pubmed/26962229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502469
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!