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Use of HLA peptidomics and whole exome sequencing to identify human immunogenic neo-antigens
The antigenicity of cells is demarcated by the peptides bound by their Human Leucocyte Antigen (HLA) molecules. Through this antigen presentation, T cell specificity response is controlled. As a fraction of the expressed mutated peptides is presented on the HLA, these neo-epitopes could be immunogen...
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| Publicado en: | Oncotarget |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868674/ https://ncbi.nlm.nih.gov/pubmed/26819371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6960 |
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