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The Effect of Proteasome Inhibition on the Generation of the Human Leukocyte Antigen (HLA) Peptidome

The Major histocompatibility complex (MHC) class I peptidome is thought to be generated mostly through proteasomal degradation of cellular proteins, a notion that is based on the alterations in presentation of selected peptides following proteasome inhibition. We evaluated the effects of proteasome...

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Detalhes bibliográficos
Main Authors: Milner, Elena, Gutter-Kapon, Lilach, Bassani-Strenberg, Michal, Barnea, Eilon, Beer, Ilan, Admon, Arie
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708171/
https://ncbi.nlm.nih.gov/pubmed/23538226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.026013
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