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The Origin of Proteasome-inhibitor Resistant HLA Class I Peptidomes: a Study With HLA-A*68:01

Some HLA class I molecules bind a significant fraction of their constitutive peptidomes in the presence of proteasome inhibitors. In this study, A*68:01-bound peptides, and their parental proteins, were characterized through massive mass spectrometry sequencing to refine its binding motif, including...

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Autors principals: García-Medel, Noel, Sanz-Bravo, Alejandro, Barnea, Eilon, Admon, Arie, López de Castro, José A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270105/
https://ncbi.nlm.nih.gov/pubmed/21969608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.011486
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