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High Resolution Longitudinal Study of HIV-1 Env Vaccine-elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence
Due to the genetic variability of the HIV-1 envelope glycoproteins (Env), the elicitation of neutralizing antibodies to conserved neutralization determinants including the primary receptor binding site, CD4 binding site (CD4bs), is a major focus of vaccine development. To gain insight into the evolu...
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| 出版年: | J Immunol |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868635/ https://ncbi.nlm.nih.gov/pubmed/27001953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502543 |
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