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Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates

Broadly neutralizing antibodies (bNAbs) against the HIV-1 envelope glycoproteins (Envs) have proven difficult to elicit by immunization. Therefore, to identify effective Env neutralization targets, efforts are underway to define the specificities of bNAbs in chronically infected individuals. For a p...

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Main Authors: Sundling, Christopher, Forsell, Mattias N.E., O'Dell, Sijy, Feng, Yu, Chakrabarti, Bimal, Rao, Srinivas S., Loré, Karin, Mascola, John R., Wyatt, Richard T., Douagi, Iyadh, Karlsson Hedestam, Gunilla B.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931166/
https://ncbi.nlm.nih.gov/pubmed/20679401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100025
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