Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates

Broadly neutralizing antibodies (bNAbs) against the HIV-1 envelope glycoproteins (Envs) have proven difficult to elicit by immunization. Therefore, to identify effective Env neutralization targets, efforts are underway to define the specificities of bNAbs in chronically infected individuals. For a p...

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Bibliographic Details
Main Authors: Sundling, Christopher, Forsell, Mattias N.E., O'Dell, Sijy, Feng, Yu, Chakrabarti, Bimal, Rao, Srinivas S., Loré, Karin, Mascola, John R., Wyatt, Richard T., Douagi, Iyadh, Karlsson Hedestam, Gunilla B.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931166/
https://ncbi.nlm.nih.gov/pubmed/20679401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100025
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