Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array

DNA sequencing by synthesis (SBS) offers a robust platform to decipher nucleic acid sequences. Recently, we reported a single-molecule nanopore-based SBS strategy that accurately distinguishes four bases by electronically detecting and differentiating four different polymer tags attached to the 5′-p...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Fuller, Carl W., Kumar, Shiv, Porel, Mintu, Chien, Minchen, Bibillo, Arek, Stranges, P. Benjamin, Dorwart, Michael, Tao, Chuanjuan, Li, Zengmin, Guo, Wenjing, Shi, Shundi, Korenblum, Daniel, Trans, Andrew, Aguirre, Anne, Liu, Edward, Harada, Eric T., Pollard, James, Bhat, Ashwini, Cech, Cynthia, Yang, Alexander, Arnold, Cleoma, Palla, Mirkó, Hovis, Jennifer, Chen, Roger, Morozova, Irina, Kalachikov, Sergey, Russo, James J., Kasianowicz, John J., Davis, Randy, Roever, Stefan, Church, George M., Ju, Jingyue
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868432/
https://ncbi.nlm.nih.gov/pubmed/27091962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601782113
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