Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array

DNA sequencing by synthesis (SBS) offers a robust platform to decipher nucleic acid sequences. Recently, we reported a single-molecule nanopore-based SBS strategy that accurately distinguishes four bases by electronically detecting and differentiating four different polymer tags attached to the 5′-p...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Fuller, Carl W., Kumar, Shiv, Porel, Mintu, Chien, Minchen, Bibillo, Arek, Stranges, P. Benjamin, Dorwart, Michael, Tao, Chuanjuan, Li, Zengmin, Guo, Wenjing, Shi, Shundi, Korenblum, Daniel, Trans, Andrew, Aguirre, Anne, Liu, Edward, Harada, Eric T., Pollard, James, Bhat, Ashwini, Cech, Cynthia, Yang, Alexander, Arnold, Cleoma, Palla, Mirkó, Hovis, Jennifer, Chen, Roger, Morozova, Irina, Kalachikov, Sergey, Russo, James J., Kasianowicz, John J., Davis, Randy, Roever, Stefan, Church, George M., Ju, Jingyue
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2016
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868432/
https://ncbi.nlm.nih.gov/pubmed/27091962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601782113
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