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Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array

DNA sequencing by synthesis (SBS) offers a robust platform to decipher nucleic acid sequences. Recently, we reported a single-molecule nanopore-based SBS strategy that accurately distinguishes four bases by electronically detecting and differentiating four different polymer tags attached to the 5′-p...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Fuller, Carl W., Kumar, Shiv, Porel, Mintu, Chien, Minchen, Bibillo, Arek, Stranges, P. Benjamin, Dorwart, Michael, Tao, Chuanjuan, Li, Zengmin, Guo, Wenjing, Shi, Shundi, Korenblum, Daniel, Trans, Andrew, Aguirre, Anne, Liu, Edward, Harada, Eric T., Pollard, James, Bhat, Ashwini, Cech, Cynthia, Yang, Alexander, Arnold, Cleoma, Palla, Mirkó, Hovis, Jennifer, Chen, Roger, Morozova, Irina, Kalachikov, Sergey, Russo, James J., Kasianowicz, John J., Davis, Randy, Roever, Stefan, Church, George M., Ju, Jingyue
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868432/
https://ncbi.nlm.nih.gov/pubmed/27091962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601782113
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