Importin 8 mediates m(7)G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E

Regulation of nuclear-cytoplasmic trafficking of oncoproteins is critical for growth homeostasis. Dysregulated trafficking contributes to malignancy, whereas understanding the process can reveal unique therapeutic opportunities. Here, we focus on eukaryotic translation initiation factor 4E (eIF4E),...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Volpon, Laurent, Culjkovic-Kraljacic, Biljana, Osborne, Michael J., Ramteke, Anup, Sun, Qingxiang, Niesman, Ashley, Chook, Yuh Min, Borden, Katherine L. B.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868427/
https://ncbi.nlm.nih.gov/pubmed/27114554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524291113
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