Structural studies of the eIF4E–VPg complex reveal a direct competition for capped RNA: Implications for translation

Viruses have transformed our understanding of mammalian RNA processing, including facilitating the discovery of the methyl-7-guanosine (m(7)G) cap on the 5′ end of RNAs. The m(7)G cap is required for RNAs to bind the eukaryotic translation initiation factor eIF4E and associate with the translation m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Coutinho de Oliveira, Luciana, Volpon, Laurent, Rahardjo, Amanda K., Osborne, Michael J., Culjkovic-Kraljacic, Biljana, Trahan, Christian, Oeffinger, Marlene, Kwok, Benjamin H., Borden, Katherine L. B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2019
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883836/
https://ncbi.nlm.nih.gov/pubmed/31712417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904752116
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