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A biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery

The eukaryotic translation initiation factor eIF4E acts in the nuclear export and translation of a subset of mRNAs. Both of these functions contribute to its oncogenic potential. While the biochemical mechanisms that underlie translation are relatively well understood, the molecular basis for eIF4E&...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Volpon, Laurent, Culjkovic-Kraljacic, Biljana, Sohn, Hye Seon, Blanchet-Cohen, Alexis, Osborne, Michael J., Borden, Katherine L.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435865/
https://ncbi.nlm.nih.gov/pubmed/28325843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.060137.116
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