Chargement en cours...
The oncogene eIF4E reprograms the nuclear pore complex to promote mRNA export and oncogenic transformation
The eukaryotic translation initiation factor eIF4E is a potent oncogene that promotes the nuclear export and translation of specific transcripts. Here, we discovered that eIF4E alters the cytoplasmic face of the nuclear pore complex (NPC) which leads to enhanced mRNA export of eIF4E target mRNAs. Sp...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463940/ https://ncbi.nlm.nih.gov/pubmed/22902403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.07.007 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|