The eukaryotic translation initiation factor eIF4E elevates steady-state m(7)G capping of coding and noncoding transcripts

Methyl-7-guanosine (m(7)G) “capping” of coding and some noncoding RNAs is critical for their maturation and subsequent activity. Here, we discovered that eukaryotic translation initiation factor 4E (eIF4E), itself a cap-binding protein, drives the expression of the capping machinery and increased ca...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Culjkovic-Kraljacic, Biljana, Skrabanek, Lucy, Revuelta, Maria V., Gasiorek, Jadwiga, Cowling, Victoria H., Cerchietti, Leandro, Borden, Katherine L. B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604501/
https://ncbi.nlm.nih.gov/pubmed/33055213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002360117
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