Molecular Mechanism for Conformational Dynamics of Ras·GTP Elucidated from In-Situ Structural Transition in Crystal

Ras•GTP adopts two interconverting conformational states, state 1 and state 2, corresponding to inactive and active forms, respectively. However, analysis of the mechanism for state transition was hampered by the lack of the structural information on wild-type Ras state 1 despite its fundamental nat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Matsumoto, Shigeyuki, Miyano, Nao, Baba, Seiki, Liao, Jingling, Kawamura, Takashi, Tsuda, Chiemi, Takeda, Azusa, Yamamoto, Masaki, Kumasaka, Takashi, Kataoka, Tohru, Shima, Fumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867591/
https://ncbi.nlm.nih.gov/pubmed/27180801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25931
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