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Structural Basis for Conformational Dynamics of GTP-bound Ras Protein
Ras family small GTPases assume two interconverting conformations, “inactive” state 1 and “active” state 2, in their GTP-bound forms. Here, to clarify the mechanism of state transition, we have carried out x-ray crystal structure analyses of a series of mutant H-Ras and M-Ras in complex with guanosi...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903345/ https://ncbi.nlm.nih.gov/pubmed/20479006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.125161 |
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