Blockade of AP-1 Potentiates Endocrine Therapy and Overcomes Resistance

The transcription factor AP-1 is downstream of growth factor (GF) receptors (GFRs) and stress-related kinases, both of which are implicated in breast cancer endocrine-resistance. Previously, we have suggested that acquired endocrine-resistance is associated with increased activity of AP-1 in an in v...

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Vydáno v:Mol Cancer Res
Hlavní autoři: Malorni, Luca, Giuliano, Mario, Migliaccio, Ilenia, Wang, Tao, Creighton, Chad J., Lupien, Mathieu, Fu, Xiaoyong, Hilsenbeck, Susan G., Healy, Nuala, De Angelis, Carmine, Mazumdar, Abhijit, Trivedi, Meghana V., Massarweh, Suleiman, Gutierrez, Carolina, De Placido, Sabino, Jeselsohn, Rinath, Brown, Myles, Brown, Powel H., Osborne, C. Kent, Schiff, Rachel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867274/
https://ncbi.nlm.nih.gov/pubmed/26965145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0423
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